ℹ️ This is the case information for the doctor.
Name
Claire Miller
Age
47
Address
14 Sweeny Road
Social history
Household: Lives with her husband, three children (two teenagers and an adult daughter), and young granddaughter. Busy, supportive family life—significant focus on looking after her granddaughter.
Occupation: Part-time care assistant;
Smoking: Non-smoker.
Alcohol: Rarely drinks
Past history
Depression (diagnosed 4 years ago; generally stable)
Hypertension (diagnosed 5 years ago; well controlled on medication)
Investigation results
FBC: Normal
U&E: Normal
LFTs: Normal
TSH: <0.01
Free T4: 49 (Normal range: 10–20)
Pulse: 94, regular
BP: 130/78
Medication
Amlodipine 5mg daily
No known drug allergies
Booking note
Last entry in records, 2 weeks ago, seen with increase in loose stools, weight loss, tremor, difficulty sleeping and palpitations,
ℹ️ This is the information for the person role playing the patient.
Name
Claire Miller
Age
47
Address
14 Sweeny Road
Social history
Household: Lives with her husband, three children (two teenagers and an adult daughter), and young granddaughter. Busy, supportive family life—significant focus on looking after her granddaughter.
Occupation: Part-time care assistant;
Smoking: Non-smoker.
Alcohol: Rarely drinks
Past history
Depression (diagnosed 4 years ago; generally stable)
Hypertension (diagnosed 5 years ago; well controlled on medication)
Medication
Amlodipine 5mg daily
No known drug allergies
I've come to get my blood results. I've really not been feeling right, so I'm hoping you can tell me what's wrong with me.
Symptoms
"I just feel worn out and knackered, it's been going on for a couple of months now."
"I'm eating and eating but still losing weight—about 5 or 6 kilos."
"People have started commenting I look thinner, even though I'm not trying to lose weight."
"My heart feels like it's racing sometimes, going much more quickly than it ever used to."
"I’m probably going to the toilet more often—the stools are looser."
Impact
"Coping with everyday has been harder as I feel more tired than normal."
Initial Presentation: Claire comes across as tired, worried, and a bit anxious but open and cooperative. She’s eager for answers, somewhat preoccupied by her symptoms and her father's cancer history.
If doctor is empathetic and takes her concerns seriously: She becomes more calm and reassured, trusts the process, accepts explanations, and is keen to follow through with management plans.
If the doctor is dismissive or vague: Anxiety and frustration increase. She becomes more insistent and possibly emotional about her worries (especially cancer).
If thyroid cancer is mentioned: She looks worried and asks directly about the risk, referencing her father’s cancer and her aunt’s thyroid operation.
If medication is offered (especially beta blocker): She accepts it if the doctor explains the benefits for her symptoms and reassures her regarding safety.
If referred to hospital/endocrinology: Claire is understanding but anxious about waiting too long and asks about how she will manage symptoms in the meantime.
If anti-thyroid drugs are discussed/offered: She is keen to start something to help her feel better but wants to know about side effects and what to expect.
If ultrasound or further blood tests are suggested: She readily agrees, showing willingness to cooperate with further investigations if it will rule out anything serious.
ℹ️ To mark data gathering & diagnosis select from the descriptors below.
Positive descriptors
Negative descriptors
Makes effective use of existing information and considers the wider context.
Fails to use the information provided or understand the wider context.
The presence or absence of relevant red flags was established.
Fails to assess key information necessary to determine risk.
Information gathered placed the problem in its psychosocial context.
The social and psychological impact of the problem was not adequately determined.
A working diagnosis was reached using a structured, evidence-based approach.
The evidence collected was inadequate to support the conclusions reached.
Revises hypotheses as necessary in light of additional information.
Rigid consulting with new information not adequately considered and integrated into the working diagnosis.
Uses an understanding of probability based on prevalence, incidence, and natural history to aid decision-making.
Choice of diagnosis and/or investigations does not reflect disease likelihood.
ℹ️ To mark clinical management & medical complexity select from the descriptors below.
Positive descriptors
Negative descriptors
Offers management options that are safe and appropriate
Fails to provide appropriate and/or safe management choices
Refers appropriately, being mindful of resource
Sends patients for specialist input unnecessarily, or omits essential referrals
Prescribes safely considering local and national guidance
Unsafe prescribing ignoring best practice
Arranges appropriate follow-up
Unclear or inadequate follow-up
Practises holistically, promoting health, and safeguarding
Fails to safeguard patient welfare
Manages uncertainty, including that experienced by the patient
Struggles with uncertainty, leading to inconsistent decisions
ℹ️ To mark relating to others select from the descriptors below.
Positive descriptors
Negative descriptors
Shows ability to communicate in a person-centred way:
Communication is doctor-centred and lacks empathy:
Treats patients fairly and with respect:
Decisions fail to prioritise the patient’s rights and interests:
Explores the patient’s agenda, health beliefs and preferences:
Fails to recognise the patient’s agenda and impact of the problem:
The patients agenda was understood:
The patients agenda was not well explored:
Demonstrates flexibility of communication adapting to the patient and scenario:
Consults rigidly, providing generic explanations and management plans:
The language and content was appropriate for the patients level of understanding:
Questions were not tailored to the patients level of understanding:
ℹ️ Insights from the examiner
References:
NICE NG145, recommendations 1.2.3–1.2.8 (Assessment)
NICE guidance on differentials includes:
NICE NG145 recommends: